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GEOLOGICAL ADVANTAGES FOR PSORIASIS SUFFERERS
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Sufferers of psoriasis have long looked to Israel and Jordan for relief of their distressing symptoms. Many
thousands of tourists descend annually on the Dead Sea for the therapeutic benefits derived from the fortunate
combination of minerals in its mud and waters, the allergen-free and bromide-rich air as well as for its filtered
Ultra Violet light. (1) (2)
Apart from its geological advantages for psoriasis sufferers, this part of the Middle East is also a world leader in
the production and study of medicinal and indigenous plants for use in complementary and alternative health care.
The hills and mountains of this region are covered with many plant species of which some 40 species are in use for
treating skin diseases by Arabic indigenous herbal practitioners based in the area. (3)
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SUPER SECRET FOR PLAQUE PSORIASIS
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SUPER SECRET Natural Healing Cream is a new product for the treatment of plaque psoriasis that has been developed in
Israel and has just become available to the American market. SUPER SECRET is based on an edible vegetative source
and is produced in a moisturizing cream format. When used twice daily it has shown excellent results in alleviating
symptoms in over seventy percent of sufferers who faithfully used the product regularly over a period of 3-4 weeks.
SUPER SECRET - CYTOSTATIC ACTION
SUPER SECRET'S mode of action inhibits cellular growth and multiplication with a marked cytostatic effect on
psoriatic plaque. The cream initially softens and soothes inflamed and irritated skin to help facilitate the release
of dead cells more efficiently. This allows SUPER SECRET to be absorbed deep into the psoriatic plaque where its
active component appears to slow-down and regulate abnormal cell turnover to help restore and balance the skin's
natural cell cycle function.
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CRUCIFEROUS CHARACTERISTICS
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SUPER SECRET Cream contains a concentrated extract from the family of edible plants known as Cruciferous
(Cruciferae) that encourages apoptosis induction on psoriatic lesions with consequent reduction in cell
proliferation. As a topical plant based formulation, the cream is well-tolerated on sensitive skin and no side
effects or untoward symptoms of any kind have been reported. (4)
The mechanism of action of cruciferous plant extract in SUPER SECRET involves an enzymatic process which once
activated converts to a number of compounds that have marked anti-proliferative and apoptosis-promoting
characteristics. (Plaque psoriasis is typified by an accelerated rate of cellular turn-over some seven times more
than normal skin.) (5)
The cruciferous plant extract in SUPER SECRET also contains a rich source of minerals as well as providing
direct-antioxidant protection through vitamins A & C. Studies have suggested that antioxidants are necessary therapy
in psoriasis as psoriatix skin is deficient and unbalanced in antioxidant activity. (6) (7)
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PSORIASIS - BREAKING THE VICIOUS CYCLE
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Psoriasis is considered an autoimmune disease and many sufferers appear to have a hereditary disposition for the
disease. However, flare-ups seem to be triggered by stress which throws the immune system out of sync to create
keratinocyte hyper-proliferation and skin inflammation. As these symptoms are in themselves a clear of stress, a
vicious cycle is consequently set in place that can exacerbate symptoms and result in a further deterioration in the
patient's condition. (9) (10)
SUPER SECRET Cream incorporates an approach to therapy which endeavors to support the patient's sesitivities and
encourages full compliance of treatment with a product that is cosmetically acceptable in its entirety. SUPER SECRET
is based on an innoucuous, edible active ingredient and its formulation is designed to offer immediate comfort to
the skin while actively reducing plaque formation. (11)
It is a fair assumption that the use of a natural and pleasent plant based alternative to strong chemical medication
such as steroids and coal tar preparations, is a factor that can contribute to breaking the vicious cycle that keeps
the condition of psoriasis in progress. (12) (13) (14)
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A HOLISTIC APPROACH FOR SKIN HEALTH
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The bioactive compound in SUPER SECRET appears to offer an important contribution to the symptomatic, topical
treatment of plaque psoriatic conditions. Nevertheless, progress will undoubtedly be enhanced when local therapy
with SUPER SECRET is combined with a detoxifying regimen to quality nutrition, mild and reqular exercise and other
stress-reducing, life-enhancing activities. (15)
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REFERENCES:
1. Climatotherapy of psoriasis and hypertension in elderly patients at the Dead-Sea. Kushelevsky AP, et al.
Pharmacol Res. 1996 Jul-Aug;34(1-2):87-91
2. Climatotherapy at the Dead Sea is a remittive therapy for psoriasis: combined effects on epidermal and
immunologic activation. Hodak E, et al. J Am Acad Dermatol. 2003 Sep;49(3):451-7
3. Ethnopharmacological survey of medicinal herbs in Israel, the Golan Heights and the West Bank region. Said O, at
el. J Ethnopharmacol. 2002 Dec;83(3):251-65
4. The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in
human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice. Pham NA, et al. Mol
Cancer Ther. 2004 Oct;3(10):1239-48
5. The new isothiocyanate 4-(methylthio)butylisothiocyanate selectively affects cell-cycle progression and apoptosis
induction of human leukemia cells. Fimognari C, et al. Invest New Drugs. 2004 Apr;22(2):119-29
6. Oxidant/antioxidant status in patients with psoriasis. Baz K, et al. Yonsei Med J. 2003 Dec 30;44(6):987-90
7. The role of oxidants and antioxidants in psoriasis. Yildirim M, et al. J Eur Acad Dermatol Venereol. 2003
Jan;17(1):34-6
8. Antioxidants and lipid perocidation status in the blood of patients with psoriasis. Kokcam I, et al. Clin Chim
Acta. 1999 Nov;289(1-2):23-31
9. Psoriasis and stress. Mark Lebwohl, Mei-Heng Tan. The Lancet, Valume 351, Number 9096, 10 January 1998
10. Psychological Distress Impairs Clearance of Psoriasis in Patients Treated With Photochemotherapy. Donal G.
Fortune, et al. Arch Dermatol. 2003;139:752-756
11. Psychiatric morbidity in psoriasis: a review. Russo PA, et al. J Eur Acad Dermatol Venereol, 2004
Jan;18(1):27-36
12. Psychological Stress Perturbs Epidermal Permeability Barrier Homeostasis Implications for the Pathogenesis of
Stress-Associated Skin Disorders. Amit Garg, et al. Arch Dermatol. 2001;137:53-59 Vol. 137 No. 1 January 2001
13. Psoriasis: the future. Kirby B, Griffiths Br J Dermatol. 2001 Apr;144 Suppl 58:37-14
14. Self-reported stress reactivity and psoriasis-related stress of Nordic psoriasis sufferers. Zachariae R, J Eur
Acad Dermatol Venereol. 2004 Jan;18(1):27-36
15. Quality of life in patients with psoriasis: the contribution of clinical variables and psoriasis-specific
stress. Fortune DG. Br J Dermatol. 1997 Nov;137(5):755-60
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These statements have not been evaluated by the Food & Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
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